How Drugs Work

How can a drug used to treat cancer be effective against viruses, too? The answer lies in the drug's shared target — specifically, cellular components that control the activity of genes. A new research study showed that one such type of drug, histone methyltransferase inhibito ...more

There has been an outbreak of syphilis in Oklahoma County with 75 confirmed cases connected by a social network driven by drug use and sex. The Oklahoma City-County Health Department (OCCHD) and the Oklahoma State Department of Health confirmed the epidemic, which infected pe ...more

What do Leo Tolstoy (writer), Beethoven (composer), Paul Gaugin (artist), and Adolf Hitler (politician) have in common? They are all considered to have suffered from the sexually transmitted disease syphilis. With the incidence of sexually transmitted infections (STIs) and se ...more

People infected with HIV take many different types of pills every day to decrease the amount of virus in their body, live a longer and healthier life, and to help prevent them from infecting others. That could all be in the past as new clinical trials testing the safety and ef ...more

Staphylococcus aureus is a widespread bacteria — about a third of us have it on our body right now — usually in our nose or on our skin. And it probably isn't causing an infection. But, about 1% of people who have Staphylococcus aureus present have a type that is resistant to ...more

Got some seriously sensitive information to keep safe and a spare-no-expenses attitude? Then the new Solarin from Sirin Labs is the smartphone for you and your $17,000. The Solarin is touted as the world's most secure smartphone. The makers of the Android-based phone packed i ...more

Natural remedies used through the ages abound, especially in Asian medicine. The willow-leaved justicia plant, found throughout Southeast Asia, has traditionally been used to treat arthritis, but scientists have just discovered it contains an anti-HIVcompound more potent than ...more

By looking for the mechanism that allows influenza A to invade lung cells, scientists also discovered a treatment that might block the virus from taking hold there. An infection of the lungs is called pneumonia, which is caused by bacteria, viruses, and fungi that target alve ...more

Gonorrhea infections reached a peak in 1975, then decreased until 2009, when infection rate started rising and has increased each year since. With the rise of antibiotic resistance, those numbers are only going to get worse — unless we find new treatments against the bacteria. ...more

Ever wonder what you look like to someone else as you walk, talk? How it looks from above, behind, or to the side? Seeing yourself in a video flattens the experience into two dimensions, but this wireless camera rig experiment from Instructables member BigRedRocket brings it i ...more

It hasn't even been eight years since Candida auris was discovered—cultured and identified from the ear canal of a patient in Japan—and now it's drug-resistant, setting up residence in hospitals, killing patients, and wreaking havoc across the globe. The yeast, C. auris, find ...more

Antibiotics are one of our main weapons against infections. The problem is that many bacteria are becoming resistant to most of the antibiotics we use to treat them, and those 'superbugs' have created an urgent threat to our global health. A research group found a new way to h ...more

Cytochrome P450 (P450s) are proteins found in nearly all living organisms, which play roles that range from producing essential compounds and hormones to metabolizing drugs and toxins. We use some of the compounds synthesized by P450 in plants as medical treatments, but the sl ...more

Coronaviruses are common viruses, and most of us catch one at some point — they cause about 30% of all common colds. A new accidental discovery could help fight these viruses, even the deadlier, emerging ones. Coronaviruses are the cause of Middle East Respiratory Syndrome (M ...more

The Centers for Disease Control and Prevention estimated that there were 212 million cases of malaria across the world in 2015, and 429,000 of those people died — mostly children living in Africa. Preventing and treating those infections has been a challenging world priority. ...more

Here is the movie trailer for the feature film "Love and Other Drugs" Here are 6 clips from the film Love and Other Drugs I Love You. Hey Lisa. Take off your clothes and jump me!. Whats your game?. A Good Salesman.

LOOK AT ME ! LOOK AT ME! LOOK AT ME! While we continue to prostitute ourselves selling shit to the masses, its good to remember the mechanism that makes it all possible. Just because its CINEMA doesn't mean we don't need television to get the message out. Had this have come o ...more

hey im jesse...whats up u guys!..listeni know there are alot of panks that have been send to you guysand most of them probably have to do with pranking one of the jackass crew...am i rightbut i think we need a new kind of prank that would be involving a real civilian ( not act ...more

Multiple airport screeners have been arrested for allegedly taking handsome bribes to look the other way while loads of illegal drugs slipped through security at Los Angeles International Airport, federal officials announced today. Two current and two former officials at the ...more

Go to a car dealership and test drive a car. Unbeknownst to the person test driving a car, stuff a bunch of fake drugs everywhere in the car and have the car salesman be an actor. Have the person test driving the car start to drive wrecklessly. A fake cop will pull him over an ...more

The Minnesota Department of Public Safety issued a press release today announcing the suspension of a drug recognition program conducted by the Minnesota State Patrol. The program was exposed earlier this month by activists and members of Communities United Against Police Brut ...more

Think you have what it takes to amputate your own arm? What about somebody else's foot? Now, thanks to the wide array of mobile apps available from the iTunes App Store, you might not need to attend medical school to perform a tracheostomy. Okay, so that's not really true—iPh ...more

For some of you out there, today may be a looooong Friday. But have no fear, if you've yet to furtively accomplish shaving off a few extra minutes from the office clock, there is an alternative for getting through the day: computer pharmaceuticals. Relax, moms, we're not talki ...more

This weekend in a jungle estuary, the DEA and local Ecuadorian police seized a prototype narco sub that may be the most sophisticated one yet. Complete with air conditioning and periscope, this 100 foot creation would have carried a more cocaine tonnage than any previously cap ...more

Apple Pay has been available to use in stores, as well as in select apps and websites, ever since its first appearance in iOS 8.1. Now, with iOS 12, there are currently 13 different iPhone models that support Apple Pay functionality without the use of an Apple Watch, and the l ...more

I've never had a black eye, but I was in a car accident that turned my entire ear dark purple a few years ago. Believe me; it was enough to get more than a few funny looks. Walking around with bruises is never fun, and it's even worse when they're on your face or neck. A blac ...more

Alcohol isn't exactly considered a healthy lifestyle choice; more often than not, it's associated with empty calories and bad decisions. But that doesn't mean there aren't a few benefits to drinking in moderation. In fact, gin is a liquor with a wealth of potential benefits to ...more

Welcome back, my novice hackers! Episode 6 of Mr. Robot has come and gone and, as usual, it did not disappoint. Once again, our hero, Elliot, has used his extraordinary intellect and hacking skills to awe and inspire us. In this episode, Elliot is being blackmailed by the ru ...more

UPDATE: The mod discussed below is no longer available for download. We are looking for an alternative and will update this page when we find one. Children grow up way too fast these days, and handing them a mini-computer in the form of a smartphone only contributes to that. ...more

It's no surprise that Costco has great deals, and that's why millions pay annual fees for the privilege to shop in their wholesale outlets. Just take their hotdog and soda combo for $1.50—it's the same price now as it was 27 years ago. The best thing about Costco is that you ...more

The next big iOS version for iPad, iPhone, and iPod touch was revealed by Apple at WWDC 2018 and dropped for everyone on Sept. 17, 2018, less than a week after Apple revealed the new iPhone lineup. We've rounded up all the big picture items and secret features and changes we c ...more

Ever see those cars so covered in dirt, dust, and grime that someone writes "Wash me" on it using their finger? Well, for those cars' sakes, as well as cases less extreme, a word of advice: procrastination is not a solution — it can only compound the problem. Self-cleaning car ...more

Montezuma's revenge, the runs, the trots, or just diarrhea — everyone gets it sooner or later. What exactly is diarrhea good for, if anything? The basic description of diarrhea is loose, watery, stools. It can be explosive, frequent, acute, or chronic — but the bottom line is ...more

After years of being a PC technician and Windows System administrator, I had the blind hatred for Apple that I thought I was suppose to have. I swore that I'd never even touch an iPod, let alone buy an Apple product. But I found a new career that drug me out of the Windows ser ...more

Your Apple Watch sends you notifications from friends, family, and the apps that are important to you. Occasionally, however, the watch may scare the heck out of you with a notification warning of an abnormal, elevated heart rate. If you have no history of heart conditions, th ...more

Coinbase is the primary go-to for many users when it comes to investing in Bitcoin (BTC), Ethereum (ETH), Litecoin (LTC), Ripple (XRP), and more, due to its user-friendly interface. But before you join them, know that the ease of use comes with a price. Coinbase charges fees f ...more

Welcome back, my novice hackers! In my series on cracking passwords, I began by showing off some basic password-cracking principles; developed an efficient password-cracking strategy; demonstrated how to use Hashcat, one of the most powerful password-cracking programs; and sh ...more

Banksy, Cope2, Invader, Retna, Mr.cartoon, They all have a few things in common. Firstly, they are all extremely talented and well known urban artists. Secondly, they all have very memorable and very, very cool names. Banksy is the most well known of the bunch, and in my opin ...more

Once we recover from the respiratory infection pneumonia, our lungs are better equipped to deal with the next infection — thanks to some special cells that take up residence there. New research led by JP Mizgerd of the Boston University School of Medicine, shows that lung tis ...more

Need to add some spooky ambient fog to your super-scary Halloween party? Rather than shelling out money for a fog machine you'll probably only use once a year, make a trip to the nearest drug store and pick up a bottle of glycerin, a gallon of distilled water, a 2-liter bottle ...more

There are nearly 100,000 unique onion service addresses online with over two million people using Tor every single day. Join me as I explore a small fraction of what the Tor network has to offer. It's puzzling to imagine about 100,000 .onion websites in existence. Readers who ...more

A mention of the deep web can bring to mind images of drugs, hackers, and other criminal activity. Despite the presence of these elements, the Tor network is a valuable tool for preserving privacy and anonymity. And browsing the deep web and any hidden services can be as simpl ...more

Frozen meat is a saving grace for weeknight meals. Whenever I crave a certain protein, all I need to do is defrost it. Sometimes, I don't even need to defrost it in order to use it. But every once in a while, I would pull a frozen chicken breast out of my freezer only to see ...more

While there are completely legitimate reasons to use Bitcoin, it's also used by terrorists, drug dealers, and other shady people that need to be investigated. That's where SpiderFoot comes in, which has a command-line interface to search for Bitcoin wallet addresses on a websi ...more

Etching your own circuit boards is tons of fun, but etching requires strong chemicals to dissolve the copper plating on blank circuit boards. The normal ferric chloride solution works well, but can be expensive and leaves permanent stains. Luckily, we can whip up our own etcha ...more

All fields of study have their own language. For people interested in learning about microbes, the language can sometimes be downright difficult — but it doesn't need to be. From antibiotics to xerophiles, we have you covered in an easy-to-understand glossary. Terms are liste ...more

I have a theory that chocolate chip cookies are the gateway drug to cooking. The recipe is easy, no special equipment is required, and at the end, you get warm, fresh-from-the-oven cookies that are simply irresistible. It's how I got hooked on baking and cooking, and anecdotal ...more

For a moment, picture a situation where you want to host some files or images, but you do not want it traced back to you. Perhaps you're working on a project with others and need secure data storage. Anonymity is the new shield of the 21st century—and you best protect yourself ...more

Codenamed "Nougat" after the sugary stuff that fills your Snickers bar, Android 7.0 is living up to its name with tons of sweet features. There's almost too many changes over Marshmallow to cover in one go, with new functionality ranging from a revamped Doze Mode for battery s ...more

Thanks to its intuitive interface that makes sending and receiving money a breeze, Venmo has become the go-to app for millions in the US. In fact, you've probably heard the term "Venmo you" being tossed around between friends. But before you take the plunge and sign up, it's a ...more

This week, Silk Road was shut down for good when the FBI seized the anonymous online marketplace after Ross Ulbricht, aka Dread Pirate Roberts, was arrested. This comes just two weeks after another illegal marketplace called Atlantis shutdown. However, there are plenty of othe ...more